What Cleanroom Design is right for you?
One-pass (also called single-pass or once-through) cleanrooms and recirculating cleanrooms are the two primary HVAC/airflow design approaches used in cleanroom construction. Both deliver HEPA-filtered air to control airborne particulates and maintain cleanliness classifications (per ISO 14644), but they differ fundamentally in how air is handled after it enters the room.
One-Pass (Single-Pass) Cleanroom
Air is drawn from the surrounding building or warehouse environment (ambient air), filtered once through ceiling-mounted HEPA fan filter units (FFUs), supplied into the cleanroom, and then exhausted directly out of the room—never returned to the cleanroom for reuse.
Airflow path:
- Ambient air → plenum above ceiling → HEPA FFUs (filters and pushes air down) → cleanroom (typically unidirectional or turbulent flow) → low-wall exhaust grilles → exhausted into the surrounding facility space.
Key characteristics:
- No dedicated air handling unit (AHU) or recirculation loop for the cleanroom.
- Temperature and humidity are not actively controlled inside the cleanroom (they follow the conditions of the surrounding space).
- The cleanroom essentially “borrows” cooling from the warehouse/building HVAC.
Recirculating Cleanroom
Air is continuously pulled from inside the cleanroom, conditioned, re-filtered, and returned. Most of the air stays in a closed loop, with only a small percentage of fresh makeup air introduced as needed for pressurization and ventilation.
Airflow path:
- Cleanroom air → low-wall returns → plenum or dedicated AHU (where it is cooled/heated, humidified/dehumidified, and pre-filtered) → HEPA filtration (terminal filters or FFUs) → supplied back into the cleanroom via ceiling diffusers or FFUs.
Key characteristics:
- Dedicated HVAC system provides precise temperature and humidity control.
- Air passes through filtration multiple times, which helps achieve lower particle counts.
- Heat loads from lighting, equipment, processes, and personnel are managed internally rather than dumped into the surrounding space.




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